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These data, together with the three published clinical trials with negative results, do not support treatment with uric acid-lowering drugs in patients with CKD to reduce progression of renal function deterioration

Some prefer to call it hypothalamicpituitaryadrenal axis dysregulation

Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors

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