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Obese patients on contrave also demonstrated significant improvements in important markers of cardiometabolic risk, including waist circumference, high-density lipoprotein cholesterol, insulin resistance and triglycerides

At the same time, more of your existing NAD+ gets consumed by enzymes like CD38 and PARPs, which are activated by things like inflammation, oxidative stress, and DNA damage

GRAS food ingredient note AOD-9604 was self-affirmed as Generally Recognized As Safe (GRAS) by an industry expert panel for limited food-ingredient use based on the Phase 1 and Phase 2 safety data

No human clinical trials have been published