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The kidney- and cardio-protective effects of semaglutide were shown in people with T2D and CKD in FLOW

Magnesium-based osmotic laxatives (magnesium hydroxide, magnesium citrate) should be used with caution, especially in older adults or those with kidney disease, due to potential for magnesium accumulation and electrolyte disturbances

These findings are consistent with previous reports showing that exposed hydrophobic surfaces on amyloidogenic aggregates mediate aberrant interactions with essential cellular proteins, leading to their sequestration and functional impairment 81

Besides being a therapeutic option for type 2 diabetes, semaglutide serves as an anti-obesity drug