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RANK Inhibitors: Osteoprotegrin and Denosumab The findings of Kondegowda and colleagues indicate that osteoprotegerin, a receptor primarily associated with bone-related functions, has the potential to promote the growth of beta cells

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Some of the released molecules, referred to as damage-associated molecular patterns (DAMPs) like heme and its derivatives, ATP, heat shock protein (HSP70), or interleukin-33 (IL-33), are capable of triggering the immune response, amplifying inflammation [62, 63]

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