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These findings indicate that adding reduced glutathione to entecavir therapy could be a highly effective approach for managing chronic hepatitis B, particularly for improving liver function and accelerating viral clearance

Oxidative stress can lead to liver cell damage, inflammation, and fibrosis progression, while GSH can alleviate these effects by supplementing intracellular antioxidant reserves and stabilizing mitochondrial function [29, 30]

Compliance data show that patients who prefer oral medications tend to maintain consistent dosing schedules better than those reluctant about injections

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