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Step-by-Step: How to Give a Subcutaneous Injection Step 1: Choose an Injection Site You can inject subcutaneously in one of three areas: Upper Arm: back of the arm, halfway between shoulder and elbow Abdomen: below the ribs, above the hip bones, and at least 2 inches from the navel Thigh: upper outer area of the front thigh Rotate injection sites each time to avoid irritation