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It is widely acknowledged within the scientific community that elevated blood glucose levels and the presence of diabetes have a detrimental effect on the production and functioning of NO

639 This pathway also endows tumor cells with abundant precursors, 640,641 which are essential for the biosynthesis of macromolecules such as lipids, nucleic acids, and proteins, thereby supporting rapid tumor growth and proliferation and inducing mesenchymal transformation

240 Notably, empagliflozin, unexpectedly gives rise to a rapid and significant elevate in TMAO levels in patients with AMI

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