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GLP-1 receptor agonists were associated with markedly lower risks of major adverse cardiovascular events, progression of kidney disease, venous thromboembolism, and all-cause mortality compared to DPP-4 inhibitor therapy

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However, no attempt was made to ascertain if the available number of patients on GLP-1 agonist use or the number of events were enough for definitive conclusions

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Since CPP-CAND was designed to interfere with the FOXO4-p53 interaction, we investigated the disruption of FOXO4-p53bp1 foci in the nucleus of senescent cells after CPP-CAND treatment

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