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Patients should also inform their healthcare provider if headaches necessitate frequent use of analgesics (more than 1015 days per month), as medication-overuse headache can develop and complicate the clinical picture

Potential Side effects The most common side effects of Tirzepatide include nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar) in patients with type 2 diabetes, flatulence (gas buildup), gastroenteritis (an intestinal infection) and gastroesophageal reflux disease (a type of digestive disorder)

TRIUMPH program design paper, Diabetes, Obesity and Metabolism , 2026 Jastreboff AM et al

Dietary treatment of the metabolic syndromethe optimal diet