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Patients should understand the difference between expected medication side effects and warning signs of potentially significant problems

Nature 365: 185188 Winter J, Klappa P, Freedman RB, Lilie H, Rudolph R (2002) Catalytic activity and chaperone function of human proteindisulfide isomerase are required for the efficient refolding of proinsulin

GLP-1 medications like tirzepatide, by contrast, activate glucagon-like peptide-1 receptors in the brain and pancreas, suppressing hunger signals, slowing gastric emptying, and improving insulin sensitivity

Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism