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10.3978/j.issn.2304-3881.2015.06.08 [DOI] [PMC free article] [PubMed] [Google Scholar] Bakan E., Taysi S., Polat M

Myosteatosis alters muscle fiber composition and organization, with a decrease in oxidative, insulin-sensitive fibers and a concomitant increase in relatively fast-fatiguing glycolytic fibers, paralleling the effects observed in obesity and aging

Additionally, Ca 2+ overload induces K + efflux through Gardos channels [187] and promotes activation of cytoskeleton-degrading calpain [188], which consequently leads to the cell shrinkage and membrane blebbing, respectively

This leads to the recruitment of neutrophils and the release of cytokines, increasing the inflammatory response