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Androgen receptor and Wnt signaling operate as key stimulators of HF development in FGF5 KO sheep To explore the causes of increased wool and active hair-follicle density in FGF5 KO sheep, we tested the expression levels of testosterone and DHT that cause androgenetic alopecia in the skin tissue of the KO and control groups by ELISA

In rodents, ID, with or without anaemia, decreased serum T4 and T3 concentrations, lowered 5-deiodinase (DIO) activity and reduced the ability to thermoregulate in response to a cold environment ( Reference Hess, Zimmermann and Arnold 39 , Reference Beard, Tobin and Green 51 Reference Beard, Finch and Green 53 )

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