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The withdrawal of blood or blood components (including by apheresis), unless performed for 1) analytical purposes including medical tests or Doping Control, or for 2) donation purposes in a collection center accredited by the relevant regulatory authority of the country in which it operates

Creatine may impact hydration status to a degree since it promotes water retention in the muscles

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From 2008-2010, Sanofi-Aventis Acomplia (selective CB1 antagonist) and Abbott Laboratories Meridia (NE/5-HT reuptake inhibitor)--both also designed to suppress appetite--were pulled from the market over similar cardiac safety concerns