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5.3 Frontiers in gene-centric therapy for riboflavin pathway disorders With the rapid advancement of gene editing, viral vectors, and mRNA-based therapeutics, targeted correction of key genes in the riboflavin pathway is breaking through the limitations of traditional vitamin supplementation, offering a transformative approach for riboflavin-responsive neurometabolic disorders

A.Martinez-SilveiraM

Consider IV vitamin cocktails

proposed a dual-induction nanosystem, Tf-LipoMof@PL, made up of a metal-organic framework (MOF) containing piperlongumine (PL) and covered with a pH-sensitive lipid layer that has been modified with transferrin