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In clinical trials (SURMOUNT programme), tirzepatide produced average weight loss of 1522% of body weight significantly greater than semaglutide (Wegovy), making it the most effective weight loss medication currently available

It isnt contagious or dangerous, and there is no permanent cure but a range of treatments (phototherapy, topical creams including JAK-inhibitors, and grafting for stable cases) can help repigment skin and slow spread