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Administration of an estimated 9 mL to a 6 kg infant or neonate is potentially capable of producing blood pressure changes

The Underdose Risk: Consistently under-dosing prevents the drug from reaching the steady-state concentration needed for weight loss, resulting in a therapeutic stall. Pharmacokinetics: The Steady State Myth The logical basis for split dosing is often the desire to avoid the trough period: the final 48 hours before the next shot when hunger returns

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Tell us a little bit about, what got you interested in metabolic health to begin with, and maybe how that led you to think about GLP-1s and so forth