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Members reported their weight on their initial medical intake questionnaire and every 3-4 weeks thereafter

1 The mMRC ranges from grade 0 (breathless with strenuous exercise only) to grade 4 (too breathless to leave house or while dressing or undressing)

Pro-inflammatory chemicals called cytokines (IL-6, TNF-) and prostaglandins contribute to fibroid growth and the heavy bleeding associated with them. Women with higher dietary inflammatory index scores show greater fibroid risk in observational data. Insulin and Insulin-Like Growth Factor Insulin resistance and hyperinsulinemia stimulate IGF-1, which acts on fibroid tissue growth receptors