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GLP-1 use in the U.S

Clinical trials show semaglutide users achieve average weight reductions of 10-15% over 68 weeks, offering a clinically validated path for those who prefer a simpler pharmacological approach

Briefly, 96-well ELISA microplates were coated with HGFR/c-MET Fc chimera (50 ng/well), blocked with 1% BSA, 5% sucrose, and 0.05% sodium azide in PBS, and then incubated for 2 h at 37C with HGF samples

After weighting the cohorts for inverse probability of treatment, the researchers found that, compared with second-line GLDs, ADRD risk was significantly lower with both GLP-1 receptor agonists (adjusted HR = 0.67