Treatment stage What may be common What deserves attention Week 1 Nausea, fullness, reduced appetite, bloating, indigestion, diarrhea, constipation, fatigue Repeated vomiting, severe pain, inability to stay hydrated Weeks 2 to 4 Early symptoms may settle, persist, or fluctuate Symptoms interfering with eating, drinking, or daily function Weeks 5 to 8 Symptoms may reappear after clinician-directed dose escalation A significant return or worsening of gastrointestinal symptoms Months 2 to 3 Some patients tolerate treatment more comfortably
Combined with dual-weight hyaluronic acid, panthenol, and allantoin to deeply hydrate, plump, and smooth the skin without heaviness
For postpartum women, many providers extend the 0.25 mg phase to six or even eight weeks, particularly if the patient is breastfeeding
Age-related muscle loss (the progressive loss of skeletal muscle mass and strength) may increase the risk of falls and has been associated with increased mortality (Clynes, Calcif Tissue Int 2015)
