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Redox disequilibrium can cause melanocyte death by activating cytotoxic T cells and other death modalities such as apoptosis, necroptosis, and necrosis or oxeiptosis [6]

Drug Metab Dispos 2003;31:117686 [DOI] [PubMed] [Google Scholar] 16.Zamek-Gliszczynski MJ, Nezasa K, Tian X, Bridges AS, Lee K, Belinsky MG, Kruh GD, Brouwer KL.Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice

Overexpression of Fas and FasL is associated with infectious complications and severity of experimental severe acute pancreatitis by promoting apoptosis of lymphocytes

They work by targeting various mechanisms in the body that regulate appetite, metabolism, and fat storage