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Some clinicians prefer to reduce the dose stepwise (for example, moving from a higher to lower maintenance dose before stopping completely) to allow for metabolic adjustment and medication changes

What evidence supports this formulation

ProRx has already recalled some of its products and acknowledged gaps in its quality controls, but the FDA made clear that it has yet to see sufficient documentation to prove that the facility has meaningfully corrected its deficiencies

However, another study found that individuals who took the weight-loss drug Orlistat in addition to carnitine supplements for 1 year lost an average of 4 pounds more than those on a regimen of Orlistat alone