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This is also why pairing it with guidance matters

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Furthermore, our own work, together with that of others, emphasizes that a moderate elevation of circulating homocysteine related to impaired homocysteine metabolism (resulting from folate deficiency or dietary methionine excess) might trigger vascular disorders by promoting vascular spasm and thrombosis (Bellamy et al, 1998

Missed Dose and Discontinuation Protocols If you forget to take a dose of the medication and remember it just before your next scheduled dose, it's best to skip the missed dose to prevent taking a double dose