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In hypercatabolic states, when the elevated demand exceeds the capacity to produce adequate amounts of this amino acid [39,40,41], the impairment of immune function may occur [37, 42]

10.1155/2018/9076485 Mediators Inflamm

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A study demonstrated that alterations in phosphatidylcholine (PC) metabolism in ARDS patients correlated with increased inflammation and oxidative stress, 50 resulting in more severe lung injury and lower levels of surfactant PC species, which contribute to alveolar collapse and heightened inflammation 51 (Figure 2)