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Wellness optimization is not a one-and-done approach

In addition, three monoclonal antibodies (mAbs) were immobilized to generate a trispecific nanobody Tri-Nab by using optimized albumin/polyester composite nanoparticles conjugated with anti-Fc antibodies, which can simultaneously target PDL1, 4-1BB, and NKG2A (or TIGIT), and can effectively bind NK cells and CD8 + T cells, inducing their activation and proliferation thereby achieving efficient tumor killing (177)

Funding Funding support was provided to TC by La Trobe University Start up Grant (20182021), Infrastructure grants (2017, 2019, 2020), and Research Focus Area grant (20182020)

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