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both agencies continue to investigate this safety signal." [26] Suicidal behavior and ideation [edit] In January 2026, the US Food and Drug Administration requested removal of suicidal behavior and ideation warning from glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications

Previous studies have reported the involvement of the 5-hydroxytryptaminergic (5-HT) system in the negative symptoms of schizophrenia (18, 68)