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These actions likely reflect improved mitochondrial function or enhanced free radical scavenging, contributing to the preservation of neural tissue ( In the metabolomic analysis of T2DM-induced DN in zebrafish larvae, the differential metabolites were predominantly enriched in pathways related to amino acid, purine and lactose metabolism

Abstract Cholesterol homeostasis is essential for healthy mammalian cells and dysregulation of cholesterol metabolism contributes to the pathogenesis of various diseases including cancer

Endocrine Abstracts

Similarly, DHODH can reduce oxidized CoQ10 by converting ubiquinone to ubiquinol within the mitochondrial inner membrane, thereby inhibiting ferroptosis [51]