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Gastroenterology 141:150156 Gier B, Matveyenko AV, Kirakossian D, Dawson D, Dry SM, Butler PC (2012) Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model

So they're willing to recommend because they're the one going to be looking at all the markers, doing the blood test and see the improvement

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Using multiple enzymes can enhance sequence coverage