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It is commonly utilised in controlled laboratory research involving melanocortin receptors (MC1RMC5R) and associated signalling pathways

Phytochemicals such as, the Resveratrol (3,4,5-trihydroxy stilbene) and the Curcuminoids (with , -unsaturated carbonyl groups) are potential inducers of HO-1 expression through Nrf2/ antioxidant-responsive element (ARE) pathway 471,472

Six of the evaluated cases included data from liver biopsies (Table 2)

Bacterial self-produced extracellular molecules such as extracellular DNA (eDNA), polysaccharides, proteins and metabolites aids them to adhere and colonize on surfaces and forms structurally stable biofilm matrix (Flemming and Wingender, 2010