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Severe or persistent vomiting that prevents food or water intake, signs of pancreatitis (upper abdominal pain radiating to the back), rapid heart rate, or signs of thyroid changes should be reported promptly

In addition to SCFAs, other gut-derived metabolites, including bile acids, 374,375,376 trimethylamine N-oxide 377,378,379,380 and indole-3-lactic acid, 380 have been linked to the pathogenesis of hypertension

Does Ivy RX require labwork before prescribing

Yes, optimising glycaemic control to individualised HbA1c targets (typically 4853 mmol/mol) is the most important intervention to slow diabetic neuropathy progression, though reversal of established nerve damage remains limited