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In the case of the developed IGF-1 MSIA-SRM, the use of the MSIA tips in comparison to beads translated into a 10-fold lower limit of detection and a 20-fold LLOQ for an extraction method requiring less than 30 minutes

Peptide solutions are far more fragile and are generally treated as short-lived even under refrigeration

Elevated ROS levels exert a paradoxical effect: while excessive ROS can be cytotoxic, moderate overproduction contributes to tumorigenesis by inflicting oxidative damage on DNA

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