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These deficiencies might manifest as fatigue, poor immunity, mood swings, or other health concerns

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Observations in rodents showed that the proximal tubule has IGF-1Rs and is responsive to IGF-1, and that renal IGF synthesis, including the collecting duct, is transiently increased in animal models of postischemic AKI, thereby providing the rationale for the use of rhGH or rhIGF-1 in AKI in order to improve kidney regeneration [3]

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Cocuzza M, Athayde KS, Agarwal A, Sharma R, Pagani R, Lucon AM, et al