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First, several of these compounds are promoted for their effects on blood vessel growth, and NPR reported FDA raised concerns about the potential to encourage cancer growth. If you have a cancer history, that is not a small footnote

While they are approved for diabetes management, insurance coverage for weight loss purposes may not be guaranteed

For starters, BPC-157 and the current crop of peptides do not seem to be obviously dangerous, in the way that Diet Coke and Twinkies and acai berries are not obviously dangerous

Peptide effects on appetite, stress response and metabolism can tangentially shift reproductive hormones