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Possible drug interactions include: Alcohol may increase the risk of lactic acidosis (Janumet) Carbonic anhydrase inhibitors such as topiramate, zonisamide, acetazolamide or dichlorphenamide may increase the risk of lactic acidosis (Janumet) Digoxin (Januvia) Insulin may increase the risk of low blood sugar (Januvia and Janumet) Share This Page: Who Am I Calling

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