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Hartikainen et al., 1992), although there are studies which have described increased (Ruberg et al., 1986), decreased (Konings et al., 1995), or normal activity (Zubenko et al., 1986
Given the reduced glutamine levels observed in the MMA group, lower NAAD may reflect impaired glutamine-dependent NAD + synthesis rather than a primary defect in NAD metabolism
From animal testing to in vitro systems: advancing standardization in microphysiological systems
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