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TABLE 6 In vivo-studies using 5 FAD and SAMP8 Mice

Together, these signaling pathways elucidate the multifaceted roles of metformin in glioma treatment, highlighting its potential as a therapeutic agent that not only induces cell death but also modifies key regulatory mechanisms within the cancer cells

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Call Your Provider Promptly For Severe abdominal pain (possible pancreatitis) Persistent vomiting that prevents fluid intake Right-upper-quadrant pain that radiates to the back or shoulder (possible gallbladder issue) Sudden vision changes (rare, but reported) Symptoms of severe dehydration: dizziness on standing, dark urine, dry mouth For a deeper dive on what to expect over time, our side effect timeline guide walks through duration and management for each common issue