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Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients

(That likely means men, though the Pentagon wont clarify.) The Endocrine Society says theres insufficient evidence for population-level screening, while one Johns Hopkins endocrinologist was more blunt: I think it is crazy. Fueled by posts on Reddit and TikTok, teens with ADHD are pairing Adderall with elaborate supplement stacks

While most people get enough in their diet, some medical conditions can cause a deficiency and others may need a supplement to help unleash the power of its positive effects

E.et al (2010b)