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Second, safety profiles of approved peptides are generally favorable, with most adverse effects being mild to moderate and manageable through appropriate clinical monitoring and patient education

Osteoblasts and osteoclasts functions are regulated by a system of neuropeptides from the central nervous system, which helps maintain the balance between bone formation and bone resorption (277)

GHK-Cu promotes angiogenesis (new blood vessel formation), which raises theoretical concerns about supporting tumor growth, though the peptide also demonstrates documented anti-cancer gene expression effects

The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews