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Kidney Function Changes and Dehydration-Related Complications GLP-1 medications can reduce kidney function indirectly through volume depletion caused by persistent vomiting and diarrhea, particularly during dose escalation phases

Individuals with heart, kidney, liver or seizure issues may require close monitoring or dosage adjustments

These included: Nausea (most frequently reported) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and transient , tending to occur during the dose escalation phase and resolving or diminishing over time

CONCERN #8: WEAKENED HAIR AND BRITTLE NAILS Description: Your hair is thinning, lacks luster, and breaks easily