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Ribas V, et al

The STEP 8 trial directly compared these two drugs and found that semaglutide achieved 15.8% weight loss compared with 6.4% for liraglutide over 68 weeks

In fact, many people with these conditions find GLP-1s helpful because hypothyroidism can make weight loss notoriously difficult

Evidence was reported according to the neuropsychiatric condition under investigation: cognitive disorders (dementia, Parkinsons disease), substance-use disorders, psychotic disorders, mood and anxiety disorders, and eating disorderseach subdivided into pre-clinical and mechanistic evidence, and clinical evidence, the latter reported following a hierarchy of evidence (that is, meta-analyses, clinical trials, observational studies, case series)