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However, a 2024 study published in Obesity recommends an evidence-based approach centered on a healthy dietary pattern that includes vegetables, fruits, whole grains, lean proteins, low-fat dairy, and healthy fats

34 Population-scale studies have also leveraged bulk RNA-seq to identify transcriptional biomarkers of aging

These FAHFAs can be stored as TAGs (156) and mobilized during cold exposure by PNPLA2 to promote de-novo lipogenesis and FA-esterification in an insulin-independent manner (157), possibly explaining the coupling of lipolysis to lipogenesis in adipocytes (151)