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Therefore, revealing the crosstalk and additional key regulators of oxidative cell death pathways is crucial for identifying new targets for drug development and screening

Several studies have demonstrated that silencing fat mass and obesity-associated protein (FTO) and iron regulatory protein 2 (IRP2) mitigates abnormalities in the amino acid antioxidant system and ferroptosis, thereby attenuating dopaminergic neuronal damage

Nevertheless, the potential involvement of other classical phagocytic cues, such as oxidized phosphatidylserines (oxPSs), warrants further rigorous investigation