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Taken together, these heterogeneous findings highlight both biological plausibility and the methodological constraints that shape the current evidence base, motivating the integrative Discussion below

Primary peptide: BPC-157 at 250 mcg orally twice daily (gut-specific delivery) Support peptide: KPV at 200 to 300 mcg orally or subcutaneously daily Implementation schedule: Weeks 1 to 4: BPC-157 orally to target gut lining repair

Many of the effects of insulin and glucose are mediated through adipocytes and adipose tissue, and the vitamin D receptor is abundantly expressed in adipocytes and is involved in their regulation (Clemente-Postigo 2015

Patients should consult their GP or specialist before considering any medication for fibromyalgia management