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In addition, as was previously reported, we observed an increase in the expression of SOD2, which is known to be involved in the mitochondrial oxidative stress pathway 14

Compare semaglutide and tirzepatide for weight loss, including effectiveness, mechanism, dosing, and side effects to help guide treatment choices

This action reduces melanin formation, resulting in a lighter skin tone over time

Initiated in 2019, the study was halted early based on a recommendation from the Independent Data Monitoring Committee after a median follow-up of 3.4 years, as it met the pre-defined efficacy criteria