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International Journal of Molecular Sciences, 17(5), p.629

even lower exposure beat placebo for weight loss in early trials. The 2.4 mg maintenance dose sits on the shoulder of the effect curve rather than at a hard ceiling

37 A preliminary study has reported that the mSHMT enzyme allows for functional redundancy in cases where activity of the cSHMT enzyme is inhibited, and is up-regulated in cells lacking cSHMT during DNA replication and repair cell phases

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