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It promotes neuroplasticity in brain regions like the hippocampus by increasing BDNF levels, glutamate release, and upregulating mGLU2 receptors, particularly in the hippocampus and prefrontal cortex
The observed increased plasma levels of 3-hydroxybutyrate and acetoacetate in IHD may indicate a metabolic adaptation in response to cardiac ischemia and impaired glucose oxidation, which force the heart toward ketone body metabolism as alternative energy source 48
30-60
The cost of GLP-1 medications to treat obesity has helped drive large increases in pharmacy trends over the last three years, and despite the clear clinical benefits of this drug class, some employers and plan sponsors have chosen to discontinue coverage due to cost concerns
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