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These genetic damages compromise stem cell function, promote abnormal mutations, and increase the risk for cancer and blood disorders ( + ratio, reduces ATP production, and disrupts fatty acid oxidation, leading to steatosis and mitochondrial injury ( By weakening the intestinal barrier, alcohol allows bacterial lipopolysaccharide (LPS) to reach the liver and activate TLR4 signaling in Kupffer cells, amplifying hepatic inflammation ( 3.2 Alcohols role in HBV pathogenesis In HBV-infected individuals, alcohol further enhances liver damage by promoting viral replication and impairing immune responses, which contributes to increased hepatitis activity

Foods high in vitamins C and E, as well as selenium, can help support your bodys natural antioxidant defenses

Wysham C, Blevins T, Arakaki R, et al

Treatment is wide surgical excision with clear margins, often combined with neck dissection if lymph nodes are involved