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It does its job by adding acetyl to the thiol group

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conducted a study on mesothelioma, also found that treatment of mesothelioma cells in culture medium with Gln deletion and depletion, the Gln uptake inhibitor V-9302, or the GLS inhibitor CB-839 significantly reduced mesothelioma cell growth by decreasing the level of expression of YAP1, the level of expression of YAP1/TEAD and its target proteins [25]

However, when given subcutaneously, GHK-Cu bypasses this barrier and the peptide gets into circulation systemically at the desired dose