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Hypertension is the most common preventable risk factor for CVDs (including coronary heart disease, heart failure, stroke, myocardial infarction, atrial fibrillation, and peripheral artery disease), chronic kidney disease, and cognitive impairment, and also the main single factor for deaths and disability worldwide (133)

Under the condition of blocking GABAergic neurotransmission, light stimulation of PPG neurons results in an increase in the excitation of MCs suggesting the involvement of PPG neurons in shaping the MC firing patterns (Thiebaud et al., 2019)

It is often noted that elevated testosterone levels can improve physical capability, support muscle development, and enhance overall athletic performance