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Specificity of a pharmacologic agent is determined and/or relies on a distinct experimental system, so specificity may differ between systems with varying dopamine receptor levels, and more specific drugs or additional mechanistic studies may be needed to precisely target a particular receptor

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Results showed that both male and female transgenic 5xFAD mice that received intranasal GHK-Cu had decreased staining intensity for MCP-1 in both brain areas (Figure 5) indicating reduced neuroinflammation levels compared to transgenic mice treated with intranasal saline