GPA attenuates IL-1 induced ferroptosis by reducing the levels of MDA, intracellular iron, and ROS, while simultaneously upregulating the expression of GSH, GPX4, and ferritin
The liver detoxifies xenobiotics and endogenous waste products through conjugation reactions, but fat metabolism (lipolysis and beta-oxidation) is regulated by insulin, glucagon, epinephrine, and adipose tissue lipase activity
Given the importance of glucose and glutamine metabolism in pancreatic cancer cells, it is not surprising that gemcitabine resistance is closely associated with metabolic status, including cellular glucose and glutamine levels
Despite being faced with many problems, it provides new directions and ideas for the treatment of myocardial injury